The effect of nocturia on sleep
Received 22 December 2009, Revised 22 March 2010, Accepted 25 March 2010, Published online 16-02-2012
Sleep Medicine Reviews Volume 15, Issue 2, Pages 91-97, April 2011
Sleep plays a vital role in physical and mental functioning. It is increasingly recognized that disturbed sleep is a highly prevalent and chronic condition that merits greater awareness due to the wide-ranging and serious repercussions associated with it. Nocturia is one of the causes of sleep disturbance and has been shown to impair functioning, quality of life, health and productivity, with those experiencing two or more voids per night reporting significant ‘bother’. Nocturia warrants full consideration as a significant target for intervention, aiming to reduce the burden of disturbed sleep on individuals, families and society. Currently, however, a definitive evaluation of the most relevant sleep endpoints in nocturia therapy is lacking. One endpoint often used is the duration of the initial sleep period, which when evaluated in combination with the number of voiding episodes per night, might be an indication of the severity of sleep disruption in patients with nocturia.
Keywords: Nocturia, Sleep, Insomnia, Quality of life.
Abbreviations: ANPatrial natriuretic peptide, CIconfidence interval, HRhazard ratio, KHQKing's Health Questionnaire, NPnocturnal polyuria, N-QoLnocturia-specific quality of life, ORodds ratio, PSQIPittsburgh Sleep Quality Index, QALYsquality-adjusted life years, QoLquality of life.
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