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Nocturia Improvement With Surgical Correction of Sleep Apnea

Park H.K. et al.

International Neurourology Journal 2016 Dec;20(4):329-334 

Commentary by Philip Van Kerrebroeck

The correlation between obstructive sleep apnoea (OSA) and nocturia is well known and established. However few studies have looked at the effect of treatment of OSA on nocturia. This study evaluates changes in nocturia after surgical correction of OSA. A total of 66 patients were included in the present study, and all had been diagnosed with OSA syndrome by polysomnography. After the diagnosis they underwent uvulopalatopharyngoplasty (UPPP). Preoperative and postoperative lower urinary tract symptoms (LUTS), quality of life (QoL), and nocturia episodes were evaluated using the International Prostate Symptom Score (IPSS) and overactive bladder symptom score (OABSS) questionnaires. Three months postoperatively, telephone interviews were performed to determine the success of surgery, current LUTS, and nocturia episodes. Patients were divided into surgical success and failure groups, with surgical success defined as snoring decrease more than 50% based on the patient's subjective judgment. The response rate for the trial was 56% , but in these success rate was 73%. In all patients, nocturia episodes significantly decreased from 1.7 ± 1.1 to 0.8 ± 1.2 (P=0.002). Mean IPSS score, OABSS score, and QoL scores were also significantly improved. The successfull group showed a significant decrease in nocturia episodes, and total IPSS, OABSS, and QoL scores. However, the failure group did not show significant changes in all parameters. OSA correction improved nocturia as well as other LUTS, but these improvements were not observed in the failure group.

This study confirms that that OSA may be a significant cause of nocturia and that nocturia as well as other LUTS can be improved by successful surgical correction of OSA.